chimeric proteins การใช้

• This allows the CBD of the chimeric protein to bind to the column.
• Frenkel-Morgenstern et al . have defined two main features of chimeric proteins.
• This enzyme from the proteobacterium " Marichromatium gracile " is a chimeric protein.
• The gene fusion produces a chimeric protein segment from which a new antigenic peptide can be derived.
• The chimeric protein is thought to associate with the nuclear corepressor / histone deacetylase complex to block hematopoietic differentiation.
• Many chimeric protein drugs are monoclonal antibodies whose specificity for a dacli-" zu "-mab.
• A "'protein domain "'is a conserved part of a given protein sequence and chimeric proteins.
• Dimers of E6, the chimeric protein, were able to bind to an E-box element ( GGCCACGTGACC ) which was recognized by other HLH proteins.
• Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma.
• Furthermore, when the temperature is lowered and the molecules described above pass through the column, the chimeric protein undergoes self-splicing and only the target protein is eluted.
• It may be a critical substrate for p210 ( bcr / abl ), a chimeric protein whose presence is associated with CML . This encoded protein binds p120 ( RasGAP ) from CML cells.
• Di-or multimeric chimeric proteins can be manufactured through genetic engineering by fusion to the original proteins of peptide domains that induce artificial protein di-or multimerization ( e . g ., streptavidin or leucine zippers ).
• Brent's use of prokaryotic repressor proteins and use of them in chimeric proteins to regulate gene expression in eukaryotes was the subject of basic patents ( including, Regulation of Eukaryotic Gene Expression, with Mark Ptashne ).
• It may be a critical substrate for p210 ( bcr / abl ), a chimeric protein whose presence is associated with CML . Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
• Protein A / G binds to all subclasses of human IgG, making it useful for purifying chimeric Protein A / G than to either Protein A or Protein G . Protein A / G also has been used for purification of macaque IgG.
• Brent's use of prokaryotic repressor proteins in eukaryotes, and development of chimeric proteins containing prokaryotic DNA binding domains, enabled identification of other transcription regulatory domains and gene regulatory technologies including tetracycline-repressor controlled transcriptional repression and the Gal4 and LexA UAS systems used in other model organisms.